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Summary

Lifecycle: draftEditUnder review
What this benchmark means
README.md

Public entries: Python and R. Passing coverage requires an installed inventory.

Goal: derive VSSEQ, VSTESTCD, VSTEST, VSORRES, VSORRESU, VSSTAT, VSREASND, VSDTC, VSTPT, VSTPTNUM, VSTPTREF and VSRFTDTC for every day of the temperature diary after each vaccination in Vital Signs (VS), including the days no temperature was entered.

Input: the vaccination log, one record per planned vaccination with its date when given; the protocol's diary period, one record per diary day with its label; and the e-diary transfer, one record per temperature entered, with its date and unit.

Variables:

  • VSSEQ numbers the subject's records by vaccination date, then diary day.
  • VSTESTCD is always TEMP.
  • VSTEST is always Temperature.
  • VSORRES is the temperature entered on the diary date, empty on a day with no entry.
  • VSORRESU is the unit of the temperature entered, empty on a day with no entry.
  • VSSTAT is NOT DONE on a diary day with no temperature entered, and empty otherwise.
  • VSREASND is NOT ENTERED on a day marked NOT DONE, and empty otherwise.
  • VSDTC is the diary date: the vaccination date on Day 1, one day later for each later diary day.
  • VSTPT is the diary day's label (DAY 1, ...).
  • VSTPTNUM is the diary day's number, 1 on the day of vaccination.
  • VSTPTREF names the vaccination the diary day follows.
  • VSRFTDTC is that vaccination's date.

Note: every vaccination that was given expects one record for each day of the diary period, whether or not the e-diary holds a temperature for it. A vaccination with no date was not given and expects no diary records.

Inputs

Under review
3 source files

input/diary_days.csv

Edit
7 rows
input/diary_days.csv
STUDYIDDIARYDAYDAYLABEL
VAX021DAY 1
VAX022DAY 2
VAX023DAY 3
VAX024DAY 4
VAX025DAY 5
VAX026DAY 6
VAX027DAY 7

input/temperature.csv

Edit
16 rows
input/temperature.csv
STUDYIDUSUBJIDTEMPDATTEMPTEMPU
VAX022023-01-0136.8C
VAX022023-01-0237.1C
VAX022023-01-0436.9C
VAX022023-01-0537.0C
VAX022023-01-0636.7C
VAX022023-01-0737.2C
VAX022023-02-2736.6C
VAX022023-02-2837.4C
VAX022023-03-0138.1C
VAX022023-03-0237.0C
VAX022023-03-0336.9C
VAX022023-03-0436.8C
VAX022023-03-0536.7C
VAX022023-03-2937.9C
VAX022023-03-0636.5C
VAX022023-03-0736.9C

input/vaccination.csv

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5 rows
input/vaccination.csv
STUDYIDUSUBJIDDOSENUMVISITVACDAT
VAX021VACCINATION 12023-01-01
VAX021VACCINATION 12023-02-27
VAX022VACCINATION 22023-03-27
VAX021VACCINATION 12023-03-06
VAX022VACCINATION 2—

Expected output

Under review
28 expected rows

expected/vs.csv

Edit
28 rows
expected/vs.csv
DOMAINSTUDYIDUSUBJIDVSSEQVSTESTCDVSTESTVSORRESVSORRESUVSSTATVSREASNDVSDTCVSTPTVSTPTNUMVSTPTREFVSRFTDTC
VSVAX021TEMPTemperature36.8C——2023-01-01DAY 11VACCINATION 12023-01-01
VSVAX022TEMPTemperature37.1C——2023-01-02DAY 22VACCINATION 12023-01-01
VSVAX023TEMPTemperature——NOT DONENOT ENTERED2023-01-03DAY 33VACCINATION 12023-01-01
VSVAX024TEMPTemperature36.9C——2023-01-04DAY 44VACCINATION 12023-01-01
VSVAX025TEMPTemperature37.0C——2023-01-05DAY 55VACCINATION 12023-01-01
VSVAX026TEMPTemperature36.7C——2023-01-06DAY 66VACCINATION 12023-01-01
VSVAX027TEMPTemperature37.2C——2023-01-07DAY 77VACCINATION 12023-01-01
VSVAX021TEMPTemperature36.6C——2023-02-27DAY 11VACCINATION 12023-02-27
VSVAX022TEMPTemperature37.4C——2023-02-28DAY 22VACCINATION 12023-02-27
VSVAX023TEMPTemperature38.1C——2023-03-01DAY 33VACCINATION 12023-02-27
VSVAX024TEMPTemperature37.0C——2023-03-02DAY 44VACCINATION 12023-02-27
VSVAX025TEMPTemperature36.9C——2023-03-03DAY 55VACCINATION 12023-02-27
VSVAX026TEMPTemperature36.8C——2023-03-04DAY 66VACCINATION 12023-02-27
VSVAX027TEMPTemperature36.7C——2023-03-05DAY 77VACCINATION 12023-02-27
VSVAX028TEMPTemperature——NOT DONENOT ENTERED2023-03-27DAY 11VACCINATION 22023-03-27
VSVAX029TEMPTemperature——NOT DONENOT ENTERED2023-03-28DAY 22VACCINATION 22023-03-27
VSVAX0210TEMPTemperature37.9C——2023-03-29DAY 33VACCINATION 22023-03-27
VSVAX0211TEMPTemperature——NOT DONENOT ENTERED2023-03-30DAY 44VACCINATION 22023-03-27
VSVAX0212TEMPTemperature——NOT DONENOT ENTERED2023-03-31DAY 55VACCINATION 22023-03-27
VSVAX0213TEMPTemperature——NOT DONENOT ENTERED2023-04-01DAY 66VACCINATION 22023-03-27
VSVAX0214TEMPTemperature——NOT DONENOT ENTERED2023-04-02DAY 77VACCINATION 22023-03-27
VSVAX021TEMPTemperature36.5C——2023-03-06DAY 11VACCINATION 12023-03-06
VSVAX022TEMPTemperature36.9C——2023-03-07DAY 22VACCINATION 12023-03-06
VSVAX023TEMPTemperature——NOT DONENOT ENTERED2023-03-08DAY 33VACCINATION 12023-03-06
VSVAX024TEMPTemperature——NOT DONENOT ENTERED2023-03-09DAY 44VACCINATION 12023-03-06
VSVAX025TEMPTemperature——NOT DONENOT ENTERED2023-03-10DAY 55VACCINATION 12023-03-06
VSVAX026TEMPTemperature——NOT DONENOT ENTERED2023-03-11DAY 66VACCINATION 12023-03-06
VSVAX027TEMPTemperature——NOT DONENOT ENTERED2023-03-12DAY 77VACCINATION 12023-03-06
Shaded columns are derived— = missing value

Human review and assessment

Your review

3 questions and your comments · View benchmark discussions

Mapping spec

Generated from the benchmark YAML; do not edit by hand

Variable NameVariable LabelTypeLengthControlled Terms or FormatOriginCoreConversion DefinitionVariable TypeVariable OrderComments for Define
DOMAINDomain AbbreviationCharAssignedSet constant value "VS".SDTM1
STUDYIDStudy IdentifierCharDerivedSet per constructed row; see the Row construction sheet.SDTM2
USUBJIDUnique Subject IdentifierCharDerivedSet per constructed row; see the Row construction sheet.SDTM3
VSTESTCDVital Signs Test Short NameCharAssignedSet constant value "TEMP".SDTM4
VSTESTVital Signs Test NameCharAssignedSet constant value "Temperature".SDTM5
VSDTCDate/Time of MeasurementsCharISO 8601DerivedSet per constructed row; see the Row construction sheet.SDTM6
VSTPTPlanned Time Point NameCharDerivedSet per constructed row; see the Row construction sheet.SDTM7
VSTPTNUMPlanned Time Point NumberNumDerivedSet per constructed row; see the Row construction sheet.SDTM8
VSTPTREFTime Point ReferenceCharDerivedSet per constructed row; see the Row construction sheet.SDTM9
VSRFTDTCDate/Time of Reference Time PointCharISO 8601DerivedSet per constructed row; see the Row construction sheet.SDTM10
VSORRESResult or Finding in Original UnitsCharDerivedTake TEMP from the TEMP record whose USUBJID equals USUBJID and TEMPDAT equals VSDTC, and no match yields blank.SDTM11
VSORRESUOriginal UnitsCharDerivedTake TEMPU from the TEMP record whose USUBJID equals USUBJID and TEMPDAT equals VSDTC, and no match yields blank.SDTM12
VSSTATCompletion StatusCharNOT DONEDerivedIf TEMP IS NULL, with TEMP taken from the TEMP record whose USUBJID equals USUBJID and TEMPDAT equals VSDTC, and no match yields blank then "NOT DONE"; otherwise blank.SDTM13
VSREASNDReason Not PerformedCharDerivedIf TEMP IS NULL, with TEMP taken from the TEMP record whose USUBJID equals USUBJID and TEMPDAT equals VSDTC, and no match yields blank then "NOT ENTERED"; otherwise blank.SDTM14
VSSEQSequence NumberNumDerivedRow number within each group of STUDYID, USUBJID, ordered by VSRFTDTC then VSTPTNUM.SDTM15
TemplateInclude whenSTUDYIDUSUBJIDVSDTCVSTPTVSTPTNUMVSTPTREFVSRFTDTC
diaryVSRFTDTC IS NOT NULLCopy STUDYID from the VAC record matching on STUDYID, where STUDYID is derived as VAC.STUDYID, and no match yields blankCopy USUBJID from the VAC record matching on STUDYID, where USUBJID is derived as VAC.USUBJID, and no match yields blankCopy DIARYDAT from the VAC record matching on STUDYID, where DIARYDAT is derived as the date VAC.VACDAT plus OFFSET days, and no match yields blankCopy DAYLABEL from the VAC record matching on STUDYID, where DAYLABEL is derived as DAYS.DAYLABEL, and no match yields blankCopy DIARYDAY from the VAC record matching on STUDYID, where DIARYDAY is derived as DAYS.DIARYDAY, and no match yields blankCopy VISIT from the VAC record matching on STUDYID, where VISIT is derived as VAC.VISIT, and no match yields blankCopy VACDAT from the VAC record matching on STUDYID, where VACDAT is derived as VAC.VACDAT, and no match yields blank
VariablePermitted values
VSSTATNOT DONE
VersionDateAuthorDescriptionReviewerSign-off
1.72026-10-20yamaa docs buildRead a specification in the 1.0 surface as its 0.5 counterpart; state that missing values stay missing where a mapping declares no missing handler, and leave out a declared missing answer that restates a handler's default
1.62026-10-17yamaa docs buildDescribe collected date parts written as ISO 8601 date text and times of day counted in seconds since midnight
1.52026-10-17yamaa docs buildName collected precision in words instead of letter codes; state imputation fallbacks, minimum source precision, bounds ignored outside the collected period, and invalid text with no handler as an error; describe date and datetime shifts, imputation flag codes, and partial text giving no date part
1.42026-10-15yamaa docs buildState datetime precision codes through the hour and minute, and complete only the time parts a collected datetime lacks
1.32026-09-29yamaa docs buildShow study codelist names, external dictionaries, and ISO 8601 formats in variable rows; list the document's codelist values and metadata
1.22026-09-29yamaa docs buildClassify ADaM copies from a declared input as Predecessor and recodes as Derived, and SDTM recodes of locally derived columns as Derived
1.12026-09-29yamaa docs buildResolve lookups into the donor record they select, and give every derivation shape a plain-language rule instead of its raw YAML
1.0yamaa docs buildInitial generation from spec.yaml

Agent prompt

The request an agent receives with the input files; each tier states no more than the one above

prompts/sdtm-vs-diary-missed-days/full.md

Edit
34 lines

Following CDISC SDTM standards, use the provided DIARY_DAYS, TEMPERATURE, and VACCINATION datasets to create a VS dataset with one record per subject per vaccination given per day of the temperature diary period.

The output dataset should contain the following columns in this order: DOMAIN, STUDYID, USUBJID, VSSEQ, VSTESTCD, VSTEST, VSORRES, VSORRESU, VSSTAT, VSREASND, VSDTC, VSTPT, VSTPTNUM, VSTPTREF, VSRFTDTC

DOMAIN is "VS". STUDYID and USUBJID are as VACCINATION gives them.

Every vaccination that was given has one record for each diary day listed in DIARY_DAYS, whether or not a temperature was entered for that day. A vaccination with no date in VACCINATION was not given and has no records.

  • VSTESTCD is "TEMP" and VSTEST is "Temperature" on every record.
  • VSTPTNUM is the diary day's number and VSTPT its label, as DIARY_DAYS gives them ("DAY 1", ...); day 1 is the day of vaccination.
  • VSTPTREF is the visit name of the vaccination the diary day follows, as VACCINATION gives it (such as "VACCINATION 1"), and VSRFTDTC is that vaccination's date.
  • VSDTC is the diary date: the vaccination date on day 1, and one calendar day later for each later diary day.
  • A temperature was entered for a diary day when TEMPERATURE holds a record for the same subject dated on that diary date.
  • VSORRES is that temperature and VSORRESU its unit, each as text exactly as TEMPERATURE writes it, so a reading written with a trailing zero keeps it. Both have no value on a diary day with no temperature entered.
  • VSSTAT is "NOT DONE" and VSREASND is "NOT ENTERED" on a diary day with no temperature entered; both have no value otherwise.
  • VSSEQ numbers each subject's records from 1, in order of vaccination date and then diary day number.

Read the source datasets from /app/input and save the completed dataset as /app/output/vs.csv.

prompts/sdtm-vs-diary-missed-days/conventions.md

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17 lines

Following CDISC SDTM standards, use the provided DIARY_DAYS, TEMPERATURE, and VACCINATION datasets to create a VS dataset with one record per subject per vaccination given per day of the temperature diary period.

The output dataset should contain the following columns in this order: DOMAIN, STUDYID, USUBJID, VSSEQ, VSTESTCD, VSTEST, VSORRES, VSORRESU, VSSTAT, VSREASND, VSDTC, VSTPT, VSTPTNUM, VSTPTREF, VSRFTDTC

DOMAIN is "VS", VSTESTCD is "TEMP" and VSTEST is "Temperature" on every record. VSTPT is a diary day label as DIARY_DAYS gives it ("DAY 1", ...); day 1 is the day of vaccination. VSTPTREF is a vaccination's visit name, such as "VACCINATION 1". VSORRES is text exactly as TEMPERATURE writes it, so a reading written with a trailing zero keeps it, or has no value. VSSTAT is "NOT DONE" or has no value, and VSREASND is "NOT ENTERED" or has no value.

Read the source datasets from /app/input and save the completed dataset as /app/output/vs.csv.

prompts/sdtm-vs-diary-missed-days/brief.md

Edit
10 lines

Following CDISC SDTM standards, use the provided DIARY_DAYS, TEMPERATURE, and VACCINATION datasets to create a VS dataset with one record per subject per vaccination given per day of the temperature diary period.

The output dataset should contain the following columns in this order: DOMAIN, STUDYID, USUBJID, VSSEQ, VSTESTCD, VSTEST, VSORRES, VSORRESU, VSSTAT, VSREASND, VSDTC, VSTPT, VSTPTNUM, VSTPTREF, VSRFTDTC

Read the source datasets from /app/input and save the completed dataset as /app/output/vs.csv.

yamaa code

Public calls generated from benchmark.yaml; results must match the expected output

R

Edit
3 lines
library(yamaa)yamaa_spec("spec.yaml")$run()$output

Python

Edit
3 lines
import yamaayamaa.spec("spec.yaml").run().output

Solution without yamaa

Written from the full prompt and the inputs alone; CI checks it reproduces the expected output

solutions/sdtm-vs-diary-missed-days/result.R

Edit
61 lines
# Reference solution for the yamaa benchmark sdtm-vs-diary-missed-days (R track).## Written from the benchmark's full prompt and its inputs alone, as an agent# would write it. Harbor's oracle agent runs it to check that the prompt can# be solved and that the grader scores a correct answer 1.suppressPackageStartupMessages({  library(dplyr)  library(readr)})read_chr <- function(path) {  read_csv(path, col_types = cols(.default = col_character()),           na = character(), trim_ws = FALSE)}diary <- read_chr("/app/input/diary_days.csv")temp  <- read_chr("/app/input/temperature.csv")vac   <- read_chr("/app/input/vaccination.csv")blank_to_na <- function(x) ifelse(is.na(x) | trimws(x) == "", NA_character_, x)diary <- diary %>%  mutate(VSTPTNUM = as.integer(DIARYDAY), VSTPT = DAYLABEL) %>%  select(STUDYID, VSTPTNUM, VSTPT)given <- vac %>%  mutate(VACDAT = blank_to_na(VACDAT)) %>%  filter(!is.na(VACDAT)) %>%  mutate(VACDATE = as.Date(VACDAT))temp <- temp %>%  mutate(TEMPDAT = blank_to_na(TEMPDAT),         TEMP = blank_to_na(TEMP),         TEMPU = blank_to_na(TEMPU)) %>%  filter(!is.na(TEMPDAT)) %>%  select(STUDYID, USUBJID, VSDTC = TEMPDAT, VSORRES = TEMP, VSORRESU = TEMPU)vs <- given %>%  inner_join(diary, by = "STUDYID", relationship = "many-to-many") %>%  mutate(VSDTC = format(VACDATE + (VSTPTNUM - 1L), "%Y-%m-%d"),         VSTPTREF = VISIT,         VSRFTDTC = VACDAT) %>%  left_join(temp, by = c("STUDYID", "USUBJID", "VSDTC")) %>%  mutate(    DOMAIN = "VS",    VSTESTCD = "TEMP",    VSTEST = "Temperature",    entered = !is.na(VSORRES),    VSSTAT = ifelse(entered, NA_character_, "NOT DONE"),    VSREASND = ifelse(entered, NA_character_, "NOT ENTERED")  ) %>%  arrange(USUBJID, VACDATE, VSTPTNUM) %>%  group_by(USUBJID) %>%  mutate(VSSEQ = row_number()) %>%  ungroup() %>%  select(DOMAIN, STUDYID, USUBJID, VSSEQ, VSTESTCD, VSTEST, VSORRES, VSORRESU,         VSSTAT, VSREASND, VSDTC, VSTPT, VSTPTNUM, VSTPTREF, VSRFTDTC)dir.create("/app/output", showWarnings = FALSE)write_csv(vs, "/app/output/vs.csv", na = "")

solutions/sdtm-vs-diary-missed-days/result.py

Edit
73 lines
# Reference solution for the yamaa benchmark sdtm-vs-diary-missed-days (Python track).## Written from the benchmark's full prompt and its inputs alone, as an agent# would write it. Harbor's oracle agent runs it to check that the prompt can# be solved and that the grader scores a correct answer 1.import csvimport datetime as dtfrom pathlib import PathINPUT = Path("/app/input")OUTPUT = Path("/app/output")COLUMNS = [    "DOMAIN", "STUDYID", "USUBJID", "VSSEQ", "VSTESTCD", "VSTEST", "VSORRES",    "VSORRESU", "VSSTAT", "VSREASND", "VSDTC", "VSTPT", "VSTPTNUM", "VSTPTREF",    "VSRFTDTC",]def read(name):    with open(INPUT / name, newline="", encoding="utf-8") as handle:        return [            {k.strip(): (v or "").strip() for k, v in row.items()}            for row in csv.DictReader(handle)        ]def main():    days = sorted(read("diary_days.csv"), key=lambda r: int(r["DIARYDAY"]))    temps = {}    for row in read("temperature.csv"):        temps.setdefault((row["USUBJID"], row["TEMPDAT"]), row)    given = [v for v in read("vaccination.csv") if v["VACDAT"]]    given.sort(key=lambda v: (v["USUBJID"], v["VACDAT"], int(v["DOSENUM"] or 0)))    records = []    seq = {}    for vac in given:        start = dt.date.fromisoformat(vac["VACDAT"])        for day in days:            num = int(day["DIARYDAY"])            date = (start + dt.timedelta(days=num - 1)).isoformat()            temp = temps.get((vac["USUBJID"], date))            seq[vac["USUBJID"]] = seq.get(vac["USUBJID"], 0) + 1            records.append({                "DOMAIN": "VS",                "STUDYID": vac["STUDYID"],                "USUBJID": vac["USUBJID"],                "VSSEQ": seq[vac["USUBJID"]],                "VSTESTCD": "TEMP",                "VSTEST": "Temperature",                "VSORRES": temp["TEMP"] if temp else "",                "VSORRESU": temp["TEMPU"] if temp else "",                "VSSTAT": "" if temp else "NOT DONE",                "VSREASND": "" if temp else "NOT ENTERED",                "VSDTC": date,                "VSTPT": day["DAYLABEL"],                "VSTPTNUM": num,                "VSTPTREF": vac["VISIT"],                "VSRFTDTC": vac["VACDAT"],            })    OUTPUT.mkdir(parents=True, exist_ok=True)    with open(OUTPUT / "vs.csv", "w", newline="", encoding="utf-8") as handle:        writer = csv.DictWriter(handle, fieldnames=COLUMNS)        writer.writeheader()        writer.writerows(records)if __name__ == "__main__":    main()

solutions/sdtm-vs-diary-missed-days/result.sas

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51 lines
/* opensas reference solution for the yamaa benchmark sdtm-vs-diary-missed-days.   Reads the benchmark inputs and derives the requested output.   Execute with the existing opensas runtime: opensas /app/output/result.sas. */data vaccination;  length STUDYID USUBJID VISIT $1024;  infile "/app/input/vaccination.csv" dsd dlm="," firstobs=2 truncover lrecl=32767;  input STUDYID : $char1024. USUBJID : $char1024. DOSENUM VISIT : $char1024. VACDAT : yymmdd10.;  /* A vaccination with no date was not given and expects no diary. */  if not missing(VACDAT);run;data diary_days;  length STUDYID DAYLABEL $1024;  infile "/app/input/diary_days.csv" dsd dlm="," firstobs=2 truncover lrecl=32767;  input STUDYID : $char1024. DIARYDAY DAYLABEL : $char1024.;run;data temperature;  length STUDYID USUBJID TEMP TEMPU $1024;  infile "/app/input/temperature.csv" dsd dlm="," firstobs=2 truncover lrecl=32767;  input STUDYID : $char1024. USUBJID : $char1024. TEMPDAT : yymmdd10. TEMP : $char1024. TEMPU : $char1024.;run;/* Each vaccination given with each diary day; Day 1 is the day of   vaccination. The entered temperature, when there is one, is matched by   subject and diary date. */proc sql;  create table expected as select v.STUDYID, v.USUBJID, v.VISIT, v.VACDAT, d.DIARYDAY, d.DAYLABEL, v.VACDAT + d.DIARYDAY - 1 as DIARYDAT from vaccination as v inner join diary_days as d on v.STUDYID=d.STUDYID;  create table joined as select e.*, t.TEMP, t.TEMPU from expected as e left join temperature as t on e.USUBJID=t.USUBJID and e.DIARYDAT=t.TEMPDAT;quit;proc sort data=joined; by STUDYID USUBJID VACDAT DIARYDAY; run;data result;  length DOMAIN $2 VSTESTCD VSTEST VSORRES VSORRESU VSSTAT VSREASND VSDTC VSTPT VSTPTREF VSRFTDTC $1024;  set joined;  by STUDYID USUBJID;  retain VSSEQ;  if first.USUBJID then VSSEQ=0;  VSSEQ+1;  DOMAIN='VS'; VSTESTCD='TEMP'; VSTEST='Temperature';  VSORRES=TEMP; VSORRESU=TEMPU; VSSTAT=''; VSREASND='';  if missing(TEMP) then do; VSSTAT='NOT DONE'; VSREASND='NOT ENTERED'; end;  VSDTC=put(DIARYDAT, yymmdd10.); VSTPT=DAYLABEL; VSTPTNUM=DIARYDAY;  VSTPTREF=VISIT; VSRFTDTC=put(VACDAT, yymmdd10.);run;proc sql;  create table final as select DOMAIN, STUDYID, USUBJID, VSSEQ, VSTESTCD, VSTEST, VSORRES, VSORRESU, VSSTAT, VSREASND, VSDTC, VSTPT, VSTPTNUM, VSTPTREF, VSRFTDTC from result;quit;proc export data=final outfile="/app/output/vs.csv" dbms=csv replace; run;