As a clinical trial statistician or programmer, challenge anything in this benchmark: describe a problem in Comments, or propose a fix with the Edit button on any source file.
- Task: Is this a specification error a study team could realistically make, and should the build stop on it rather than continue?
- Inputs: Do they trigger the failure for the reason the summary gives?
- Expected failure: Is this the right error, raised at the right point, and would it tell the programmer what to fix?
The other tabs beside Comments are background for assessment, not under review.
Summary
README.mdGoal: work out PCHG, the percent change from baseline, from
the collected result in AVAL and its baseline in BASE.
Input: laboratory results with baseline values from LB,
carrying the collected numeric result (LBSTRESN) and the
baseline it is compared with (LBBLRESN).
Variables:
AVALwould be the collected numeric result, taken fromLBSTRESN.BASEwould be the baseline it is compared with, taken fromLBBLRESN.PCHGwould be the change from baseline as a percentage of it, worked out as100 * (AVAL - BASE) / BASE; missing when either value is missing.
Note: a zero baseline leaves the percentage with no value. Leaving it missing would assume a rule the request never stated, so the run fails and no artifact is accepted.
How to fix
If the intended result is missing when BASE is zero, guard the denominator
explicitly with NULLIF:
derivation:
compute:
expr: "100 * (AVAL - BASE) / NULLIF(BASE, 0)"
NULLIF(BASE, 0) returns missing for a zero baseline. Missing then propagates
through the division, so PCHG is missing for that row instead of raising
division_by_zero; nonzero baselines retain the original calculation.
Expected failure
Editthe run is rejected; no artifact is acceptedexpected/error.yaml- phase
- derivation
- condition
- division_by_zero
- requirement
- REQ-0430
expected/error.yaml
phase: derivation
condition: division_by_zero
spec_paths:
- columns.PCHG.derivation.compute
requirement: REQ-0430
context:
expr: "100 * (AVAL - BASE) / BASE"
keys:
- STUDYID: PILOT7
USUBJID: P7-742
PARAMCD: ALT
Inputs
Under review1 source fileinput/lb.csv
Edit2 rows| STUDYID | USUBJID | LBTESTCD | LBSTRESN | LBBLRESN |
|---|---|---|---|---|
| PILOT7 | ALT | 42 | 35 | |
| PILOT7 | ALT | 38 | 0 |
Unexpected Output
Under reviewNo artifact is producedNo fixture files in this directory.
Comments and assessment materials
| Dataset Name | Variable Name | Variable Label | Type | Codelist/Controlled Terms | Core | Computational Method | Origin |
|---|---|---|---|---|---|---|---|
| ADLB | STUDYID | Study Identifier | character | Copy value from LB.STUDYID. | Predecessor | ||
| ADLB | USUBJID | Unique Subject Identifier | character | Copy value from LB.USUBJID. | Predecessor | ||
| ADLB | PARAMCD | Parameter Code | character | Copy value from LB.LBTESTCD. | Predecessor | ||
| ADLB | AVAL | Analysis Value | numeric | Copy value from LB.LBSTRESN. | Predecessor | ||
| ADLB | BASE | Baseline Value | numeric | Copy value from LB.LBBLRESN. | Predecessor | ||
| ADLB | PCHG | Percent Change from Baseline | numeric | Compute 100 * (AVAL - BASE) / BASE. | Derived |
| Version | Date | Author | Description | Reviewer | Sign-off |
|---|---|---|---|---|---|
| 1.3 | 2026-09-29 | yamaa docs build | Show study codelist names, external dictionaries, and ISO 8601 formats in variable rows; list the document's codelist values and metadata | ||
| 1.2 | 2026-09-29 | yamaa docs build | Classify ADaM copies from a declared input as Predecessor and recodes as Derived, and SDTM recodes of locally derived columns as Derived | ||
| 1.1 | 2026-09-29 | yamaa docs build | Resolve lookups into the donor record they select, and give every derivation shape a plain-language rule instead of its raw YAML | ||
| 1.0 | yamaa docs build | Initial generation from spec.yaml |
yamaa
Comments
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