As a clinical trial statistician or programmer, challenge anything in this benchmark: describe a problem in Comments, or propose a fix with the Edit button on any source file.
- Task: Would a real study need this derivation, specified this way? Does it follow CDISC ADaM: variable names, controlled terms, record structure? Flag any rule that is ambiguous or that a sponsor would handle differently.
- Inputs: Do they look like data collected in a real trial, and do they include the situations you would expect to meet in one?
- Expected output: Would independent QC programming reproduce every value from these inputs and rules?
The other tabs beside Comments are background for assessment, not under review.
Summary
README.mdGoal: add one mean arterial pressure (MAP) record, holding the result
in AVAL and CALCULATION in DTYPE, for each subject and visit that has
both a systolic (SYSBP) and a diastolic (DIABP) blood pressure result;
every collected record stays in the data.
Input: vital-signs records carrying a collected result (AVAL) for
systolic (SYSBP) and diastolic (DIABP) blood pressure, one record per
subject, visit, and parameter.
Variables:
AVAL: the collected result, or two-thirds of the diastolic pressure plus one-third of the systolic pressure on the added record. No record is added when either contributor is absent from the visit or its result is missing.DTYPE:CALCULATIONon the added record and blank on collected records.
Note: a subject and visit with more than one SYSBP or DIABP record
stops the run rather than choosing one, and so does an input that already
carries a MAP record.
Inputs
Under review1 source fileinput/advs.csv
Edit9 rows| STUDYID | USUBJID | PARAMCD | PARAM | AVAL | VISIT |
|---|---|---|---|---|---|
| YAMAA-01 | SYSBP | Systolic Blood Pressure (mmHg) | 121 | BASELINE | |
| YAMAA-01 | DIABP | Diastolic Blood Pressure (mmHg) | 81 | BASELINE | |
| YAMAA-01 | SYSBP | Systolic Blood Pressure (mmHg) | 118 | WEEK 2 | |
| YAMAA-01 | DIABP | Diastolic Blood Pressure (mmHg) | 78 | WEEK 2 | |
| YAMAA-01 | SYSBP | Systolic Blood Pressure (mmHg) | 90 | BASELINE | |
| YAMAA-01 | DIABP | Diastolic Blood Pressure (mmHg) | 60 | BASELINE | |
| YAMAA-01 | SYSBP | Systolic Blood Pressure (mmHg) | 110 | BASELINE | |
| YAMAA-01 | SYSBP | Systolic Blood Pressure (mmHg) | 125 | BASELINE | |
| YAMAA-01 | DIABP | Diastolic Blood Pressure (mmHg) | — | BASELINE |
Expected output
Under review12 expected rowsexpected/advs.csv
Edit12 rows| STUDYID | USUBJID | PARAMCD | PARAM | AVAL | VISIT | DTYPE |
|---|---|---|---|---|---|---|
| YAMAA-01 | SYSBP | Systolic Blood Pressure (mmHg) | 121 | BASELINE | — | |
| YAMAA-01 | DIABP | Diastolic Blood Pressure (mmHg) | 81 | BASELINE | — | |
| YAMAA-01 | SYSBP | Systolic Blood Pressure (mmHg) | 118 | WEEK 2 | — | |
| YAMAA-01 | DIABP | Diastolic Blood Pressure (mmHg) | 78 | WEEK 2 | — | |
| YAMAA-01 | SYSBP | Systolic Blood Pressure (mmHg) | 90 | BASELINE | — | |
| YAMAA-01 | DIABP | Diastolic Blood Pressure (mmHg) | 60 | BASELINE | — | |
| YAMAA-01 | SYSBP | Systolic Blood Pressure (mmHg) | 110 | BASELINE | — | |
| YAMAA-01 | SYSBP | Systolic Blood Pressure (mmHg) | 125 | BASELINE | — | |
| YAMAA-01 | DIABP | Diastolic Blood Pressure (mmHg) | — | BASELINE | — | |
| YAMAA-01 | MAP | Mean Arterial Pressure (mmHg) | 94.33333333333333 | BASELINE | CALCULATION | |
| YAMAA-01 | MAP | Mean Arterial Pressure (mmHg) | 91.33333333333333 | WEEK 2 | CALCULATION | |
| YAMAA-01 | MAP | Mean Arterial Pressure (mmHg) | 70 | BASELINE | CALCULATION |
Comments and assessment materials
| Dataset Name | Variable Name | Variable Label | Type | Codelist/Controlled Terms | Core | Computational Method | Origin |
|---|---|---|---|---|---|---|---|
| ADVS | STUDYID | Study Identifier | character | Copy value from ADVS_RAW.STUDYID. | Predecessor | ||
| ADVS | USUBJID | Unique Subject Identifier | character | Copy value from ADVS_RAW.USUBJID. | Predecessor | ||
| ADVS | PARAMCD | Parameter Code | character | Set per constructed row; see the Row construction sheet. | Derived | ||
| ADVS | PARAM | Parameter | character | Set per constructed row; see the Row construction sheet. | Derived | ||
| ADVS | AVAL | Analysis Value | numeric | Set per constructed row; see the Row construction sheet. | Derived | ||
| ADVS | VISIT | Visit Name | character | Copy value from ADVS_RAW.VISIT. | Predecessor | ||
| ADVS | DTYPE | Derivation Type | character | Set per constructed row; see the Row construction sheet. | Derived |
| Template | Include when | PARAMCD | PARAM | SYSBP_VAL | DIABP_VAL | AVAL | DTYPE |
|---|---|---|---|---|---|---|---|
| collected | Copy ADVS_RAW.PARAMCD | Copy ADVS_RAW.PARAM | Constant "None" | Constant "None" | Copy ADVS_RAW.AVAL | Constant "None" | |
| derived_map | SYSBP_VAL IS NOT NULL AND DIABP_VAL IS NOT NULL | Constant "MAP" | Constant "Mean Arterial Pressure (mmHg)" | Aggregate ONLY(ADVS_RAW.AVAL) over records matching on the shared output keys, where ADVS_RAW.PARAMCD = 'SYSBP' | Aggregate ONLY(ADVS_RAW.AVAL) over records matching on the shared output keys, where ADVS_RAW.PARAMCD = 'DIABP' | Compute (2 * DIABP_VAL + SYSBP_VAL) / 3 | Constant "CALCULATION" |
| Version | Date | Author | Description | Reviewer | Sign-off |
|---|---|---|---|---|---|
| 1.3 | 2026-09-29 | yamaa docs build | Show study codelist names, external dictionaries, and ISO 8601 formats in variable rows; list the document's codelist values and metadata | ||
| 1.2 | 2026-09-29 | yamaa docs build | Classify ADaM copies from a declared input as Predecessor and recodes as Derived, and SDTM recodes of locally derived columns as Derived | ||
| 1.1 | 2026-09-29 | yamaa docs build | Resolve lookups into the donor record they select, and give every derivation shape a plain-language rule instead of its raw YAML | ||
| 1.0 | yamaa docs build | Initial generation from spec.yaml |
prompts/adam-advs-map/full.md
Edit22 linesFollowing CDISC ADaM standards, use the provided ADVS_RAW dataset to create an ADVS dataset with one record per subject per visit per parameter.
The output dataset should contain the following columns in this order: STUDYID, USUBJID, PARAMCD, PARAM, AVAL, VISIT, DTYPE
Keep every collected record, and add one mean arterial pressure record for each subject and visit that has both a systolic and a diastolic blood pressure result. Mark it with PARAMCD "MAP" and PARAM "Mean Arterial Pressure (mmHg)".
AVAL keeps each collected result. On the added record it is the average that counts the diastolic pressure twice and the systolic pressure once, not rounded. No record is added when either contributor is absent from the visit or its result is missing.
DTYPE is CALCULATION on the added record and has no value on collected records.
Read the source datasets from /app/input and save the completed dataset as /app/output/advs.csv.
prompts/adam-advs-map/conventions.md
Edit16 linesFollowing CDISC ADaM standards, use the provided ADVS_RAW dataset to create an ADVS dataset with one record per subject per visit per parameter.
The output dataset should contain the following columns in this order: STUDYID, USUBJID, PARAMCD, PARAM, AVAL, VISIT, DTYPE
Mark a mean arterial pressure record with PARAMCD "MAP" and PARAM "Mean Arterial Pressure (mmHg)".
On a mean arterial pressure record AVAL is not rounded.
DTYPE is CALCULATION or has no value.
Read the source datasets from /app/input and save the completed dataset as /app/output/advs.csv.
prompts/adam-advs-map/brief.md
Edit9 linesFollowing CDISC ADaM standards, use the provided ADVS_RAW dataset to create an ADVS dataset with one record per subject per visit per parameter.
The output dataset should contain the following columns in this order: STUDYID, USUBJID, PARAMCD, PARAM, AVAL, VISIT, DTYPE
Read the source datasets from /app/input and save the completed dataset as /app/output/advs.csv.
run.R
Edit4 lineslibrary(yamaa)advs <- yamaa_domain("spec.yaml")$outputadvsrun.py
Edit4 linesimport yamaaadvs = yamaa.yamaa_domain("spec.yaml").outputadvssolutions/adam-advs-map/result.R
Edit45 lines# Reference solution for the yamaa benchmark adam-advs-map (R track).## Written from the benchmark's full prompt and its inputs alone, as an agent# would write it. Harbor's oracle agent runs it to check that the prompt can# be solved and that the grader scores a correct answer 1.library(dplyr, warn.conflicts = FALSE)library(readr)raw <- read_csv( "/app/input/advs.csv", col_types = cols(AVAL = col_double(), .default = col_character()))# Every collected record stays in place.collected <- raw |> transmute(STUDYID, USUBJID, PARAMCD, PARAM, AVAL, VISIT, DTYPE = NA_character_)# The visit's systolic and diastolic results.sysbp <- raw |> filter(PARAMCD %in% "SYSBP", !is.na(AVAL)) |> group_by(STUDYID, USUBJID, VISIT) |> summarise(SYSBP_VAL = first(AVAL), .groups = "drop")diabp <- raw |> filter(PARAMCD %in% "DIABP", !is.na(AVAL)) |> group_by(STUDYID, USUBJID, VISIT) |> summarise(DIABP_VAL = first(AVAL), .groups = "drop")# One mean arterial pressure record for each visit with both results,# counting the diastolic pressure twice.map_records <- sysbp |> inner_join(diabp, by = c("STUDYID", "USUBJID", "VISIT")) |> transmute( STUDYID, USUBJID, PARAMCD = "MAP", PARAM = "Mean Arterial Pressure (mmHg)", AVAL = (SYSBP_VAL + 2 * DIABP_VAL) / 3, VISIT, DTYPE = "CALCULATION" )advs <- bind_rows(collected, map_records) |> arrange(USUBJID, VISIT, PARAMCD)dir.create("/app/output", showWarnings = FALSE)write_csv(advs, "/app/output/advs.csv", na = "")solutions/adam-advs-map/result.py
Edit59 lines# Reference solution for the yamaa benchmark adam-advs-map (Python track).## Written from the benchmark's full prompt and its inputs alone, as an agent# would write it. Harbor's oracle agent runs it to check that the prompt can# be solved and that the grader scores a correct answer 1.from pathlib import Pathimport polars as plraw = pl.read_csv("/app/input/advs.csv", infer_schema=False).with_columns( pl.col("AVAL").cast(pl.Float64, strict=False))# Every collected record stays in place.collected = raw.select( "STUDYID", "USUBJID", "PARAMCD", "PARAM", "AVAL", "VISIT", DTYPE=pl.lit(None, dtype=pl.String),)# The visit's systolic and diastolic results.sysbp = ( raw.filter( (pl.col("PARAMCD") == "SYSBP") & pl.col("AVAL").is_not_null() ) .group_by(["STUDYID", "USUBJID", "VISIT"]) .agg(SYSBP_VAL=pl.col("AVAL").first()))diabp = ( raw.filter( (pl.col("PARAMCD") == "DIABP") & pl.col("AVAL").is_not_null() ) .group_by(["STUDYID", "USUBJID", "VISIT"]) .agg(DIABP_VAL=pl.col("AVAL").first()))# One mean arterial pressure record for each visit with both results,# counting the diastolic pressure twice.map_records = ( sysbp.join(diabp, on=["STUDYID", "USUBJID", "VISIT"], how="inner") .with_columns(AVAL=(pl.col("SYSBP_VAL") + 2 * pl.col("DIABP_VAL")) / 3) .select( "STUDYID", "USUBJID", "AVAL", "VISIT", PARAMCD=pl.lit("MAP"), PARAM=pl.lit("Mean Arterial Pressure (mmHg)"), DTYPE=pl.lit("CALCULATION"), ) .select("STUDYID", "USUBJID", "PARAMCD", "PARAM", "AVAL", "VISIT", "DTYPE"))advs = pl.concat([collected, map_records], how="diagonal").sort( ["USUBJID", "VISIT", "PARAMCD"])Path("/app/output").mkdir(parents=True, exist_ok=True)advs.write_csv("/app/output/advs.csv")solutions/adam-advs-map/result.sas
Edit21 lines/* opensas reference solution for the yamaa benchmark adam-advs-map. Reads the benchmark inputs and derives the requested output. Execute with the existing opensas runtime: opensas /app/output/result.sas. */data advs; length STUDYID USUBJID PARAMCD PARAM VISIT $1024; infile "/app/input/advs.csv" dsd dlm="," firstobs=2 truncover lrecl=32767; input STUDYID : $char1024. USUBJID : $char1024. PARAMCD : $char1024. PARAM : $char1024. AVAL VISIT : $char1024.;run;proc sql; create table computed as select a.STUDYID,a.USUBJID,'MAP' as PARAMCD,'Mean Arterial Pressure (mmHg)' as PARAM,(a.AVAL+2*b.AVAL)/3 as AVAL,a.VISIT,'CALCULATION' as DTYPE from advs as a inner join advs as b on a.STUDYID=b.STUDYID and a.USUBJID=b.USUBJID and a.VISIT=b.VISIT where a.PARAMCD='SYSBP' and b.PARAMCD='DIABP' and not missing(a.AVAL) and not missing(b.AVAL);quit;data collected; length DTYPE $11; set advs; run;data result; set collected computed; run;proc sql; create table final as select STUDYID, USUBJID, PARAMCD, PARAM, AVAL, VISIT, DTYPE from result;quit;proc export data=final outfile="/app/output/advs.csv" dbms=csv replace; run;
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