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Summary
README.mdPublic entries: Python and R. Passing coverage requires an installed inventory.
Goal: carry each subject's first rescue medication in RESCTRT.
Input: one subject-level table listing the subjects, plus
medication records carrying a treatment name (CMTRT), a category
(CMCAT), a start date (CMSTDTC), and a sequence number (CMSEQ).
Variables:
RESCTRTis the treatment name of the subject's first rescue medication: a record whose category (CMCAT) isRESCUE MEDICATION, picked by the earliest start date (CMSTDTC), with the smaller sequence number (CMSEQ) breaking a tie. It is left blank, never filled with placeholder text, when the subject took no rescue medication, whether the subject took other medications or has no medication records at all. A rescue record with no recorded start date still counts; a duplicated record does not change the answer. A start date with only year and month compares as written, so it falls before any full date in the same month.
Inputs
Under review2 source filesinput/cm.csv
Edit14 rows| STUDYID | USUBJID | CMSEQ | CMTRT | CMCAT | CMSTDTC |
|---|---|---|---|---|---|
| YAMAA-01 | 1 | LISINOPRIL | CONCOMITANT MEDICATION | 2025-02-10 | |
| YAMAA-01 | 2 | DEXAMETHASONE | RESCUE MEDICATION | 2025-03-20 | |
| YAMAA-01 | 3 | PREDNISONE | RESCUE MEDICATION | 2025-03-05 | |
| YAMAA-01 | 4 | NAPROXEN | RESCUE MEDICATION | 2025-03 | |
| YAMAA-01 | 1 | ATORVASTATIN | CONCOMITANT MEDICATION | 2025-02-15 | |
| YAMAA-01 | 2 | METFORMIN | CONCOMITANT MEDICATION | 2025-03-01 | |
| YAMAA-01 | 1 | ALBUTEROL | RESCUE MEDICATION | 2025-04-01 | |
| YAMAA-01 | 2 | SALBUTAMOL | RESCUE MEDICATION | 2025-04-01 | |
| YAMAA-01 | 3 | OMEPRAZOLE | CONCOMITANT MEDICATION | 2025-03-15 | |
| YAMAA-01 | 1 | ONDANSETRON | RESCUE MEDICATION | 2025-05-12 | |
| YAMAA-01 | 1 | ONDANSETRON | RESCUE MEDICATION | 2025-05-12 | |
| YAMAA-01 | 2 | LEVOTHYROXINE | CONCOMITANT MEDICATION | 2025-02-20 | |
| YAMAA-01 | 1 | LOPERAMIDE | RESCUE MEDICATION | — | |
| YAMAA-01 | 2 | IBUPROFEN | CONCOMITANT MEDICATION | 2025-06-01 |
input/dm.csv
Edit6 rows| STUDYID | USUBJID |
|---|---|
| YAMAA-01 | |
| YAMAA-01 | |
| YAMAA-01 | |
| YAMAA-01 | |
| YAMAA-01 | |
| YAMAA-01 |
Expected output
Under review6 expected rowsexpected/adsl.csv
Edit6 rows| STUDYID | USUBJID | RESCTRT |
|---|---|---|
| YAMAA-01 | NAPROXEN | |
| YAMAA-01 | — | |
| YAMAA-01 | ALBUTEROL | |
| YAMAA-01 | ONDANSETRON | |
| YAMAA-01 | — | |
| YAMAA-01 | LOPERAMIDE |
Human review and assessment
| Dataset Name | Variable Name | Variable Label | Type | Codelist/Controlled Terms | Core | Computational Method | Origin |
|---|---|---|---|---|---|---|---|
| ADSL | STUDYID | Study Identifier | character | Copy value from DM.STUDYID. | Predecessor | ||
| ADSL | USUBJID | Unique Subject Identifier | character | Copy value from DM.USUBJID. | Predecessor | ||
| ADSL | RESCTRT | Rescue Medication | character | Copy value from CM.CMTRT where CM.CMCAT = 'RESCUE MEDICATION', keeping the first ordered by CM.CMSTDTC then CM.CMSEQ. | Predecessor |
| Version | Date | Author | Description | Reviewer | Sign-off |
|---|---|---|---|---|---|
| 1.7 | 2026-10-20 | yamaa docs build | Read a specification in the 1.0 surface as its 0.5 counterpart; state that missing values stay missing where a mapping declares no missing handler, and leave out a declared missing answer that restates a handler's default | ||
| 1.6 | 2026-10-17 | yamaa docs build | Describe collected date parts written as ISO 8601 date text and times of day counted in seconds since midnight | ||
| 1.5 | 2026-10-17 | yamaa docs build | Name collected precision in words instead of letter codes; state imputation fallbacks, minimum source precision, bounds ignored outside the collected period, and invalid text with no handler as an error; describe date and datetime shifts, imputation flag codes, and partial text giving no date part | ||
| 1.4 | 2026-10-15 | yamaa docs build | State datetime precision codes through the hour and minute, and complete only the time parts a collected datetime lacks | ||
| 1.3 | 2026-09-29 | yamaa docs build | Show study codelist names, external dictionaries, and ISO 8601 formats in variable rows; list the document's codelist values and metadata | ||
| 1.2 | 2026-09-29 | yamaa docs build | Classify ADaM copies from a declared input as Predecessor and recodes as Derived, and SDTM recodes of locally derived columns as Derived | ||
| 1.1 | 2026-09-29 | yamaa docs build | Resolve lookups into the donor record they select, and give every derivation shape a plain-language rule instead of its raw YAML | ||
| 1.0 | yamaa docs build | Initial generation from spec.yaml |
prompts/adam-adsl-rescue-med/full.md
Edit19 linesFollowing CDISC ADaM standards, use the provided CM and DM datasets to create an ADSL dataset with one record per subject.
The output dataset should contain the following columns in this order: STUDYID, USUBJID, RESCTRT
RESCTRT is the treatment name (CMTRT) of the subject's first rescue medication: a CM record whose category (CMCAT) is "RESCUE MEDICATION", chosen by the earliest start date (CMSTDTC), with the smaller CMSEQ breaking a tie between records with the same start date. RESCTRT has no value when the subject took no rescue medication, whether the subject took other medications or has no medication records at all, and it is never filled with placeholder text. A rescue record with no recorded start date still counts. A duplicated rescue record does not change the answer. A start date recorded with only a year and month compares as written, so it falls before any full date in the same month.
Read the source datasets from /app/input and save the completed dataset as /app/output/adsl.csv.
prompts/adam-adsl-rescue-med/conventions.md
Edit12 linesFollowing CDISC ADaM standards, use the provided CM and DM datasets to create an ADSL dataset with one record per subject.
The output dataset should contain the following columns in this order: STUDYID, USUBJID, RESCTRT
RESCTRT is the treatment name (CMTRT) of the subject's first rescue medication, or has no value, and it is never filled with placeholder text.
Read the source datasets from /app/input and save the completed dataset as /app/output/adsl.csv.
prompts/adam-adsl-rescue-med/brief.md
Edit8 linesFollowing CDISC ADaM standards, use the provided CM and DM datasets to create an ADSL dataset with one record per subject.
The output dataset should contain the following columns in this order: STUDYID, USUBJID, RESCTRT
Read the source datasets from /app/input and save the completed dataset as /app/output/adsl.csv.
R
Edit3 lineslibrary(yamaa)yamaa_spec("spec.yaml")$run()$outputPython
Edit3 linesimport yamaayamaa.spec("spec.yaml").run().outputsolutions/adam-adsl-rescue-med/result.R
Edit36 lines# Reference solution for the yamaa benchmark adam-adsl-rescue-med (R track).## Written from the benchmark's full prompt and its inputs alone, as an agent# would write it. Harbor's oracle agent runs it to check that the prompt can# be solved and that the grader scores a correct answer 1.library(dplyr, warn.conflicts = FALSE)library(readr)dm <- read_csv( "/app/input/dm.csv", col_types = cols(.default = col_character()))cm <- read_csv( "/app/input/cm.csv", col_types = cols(CMSEQ = col_integer(), .default = col_character()))# The first rescue medication by earliest start date, with the smaller# sequence number breaking a tie. A start holding only year and month# compares as written, so it falls before any full date in the same# month; a record with no start date still counts.first <- cm |> filter(CMCAT == "RESCUE MEDICATION") |> mutate(sortkey = coalesce(CMSTDTC, "")) |> arrange(sortkey, CMSEQ) |> distinct(STUDYID, USUBJID, .keep_all = TRUE) |> select(STUDYID, USUBJID, RESCTRT = CMTRT)adsl <- dm |> left_join(first, by = c("STUDYID", "USUBJID")) |> select(STUDYID, USUBJID, RESCTRT) |> arrange(USUBJID)dir.create("/app/output", showWarnings = FALSE)write_csv(adsl, "/app/output/adsl.csv", na = "")solutions/adam-adsl-rescue-med/result.py
Edit56 lines# Reference solution for the yamaa benchmark adam-adsl-rescue-med (Python track).## Written from the benchmark's full prompt and its inputs alone, as an agent# would write it. Harbor's oracle agent runs it to check that the prompt can# be solved and that the grader scores a correct answer 1.import csvfrom pathlib import PathINPUT = Path("/app/input")OUTPUT = Path("/app/output")def read_rows(name): with open(INPUT / name, newline="", encoding="utf-8") as f: return list(csv.DictReader(f))def main(): dm = read_rows("dm.csv") cm = read_rows("cm.csv") rescue = {} for row in cm: if (row.get("CMCAT") or "") != "RESCUE MEDICATION": continue key = (row.get("STUDYID") or "", row.get("USUBJID") or "") # Compare the start date as written: a year-month value such as # "2025-03" sorts before any full date in the same month under # plain string ordering. A missing date sorts as the empty string. date_key = row.get("CMSTDTC") or "" try: seq_key = int(row.get("CMSEQ") or "") except ValueError: try: seq_key = float(row.get("CMSEQ") or "") except ValueError: seq_key = 0 sort_key = (date_key, seq_key) if key not in rescue or sort_key < rescue[key][0]: rescue[key] = (sort_key, row.get("CMTRT") or "") OUTPUT.mkdir(parents=True, exist_ok=True) with open(OUTPUT / "adsl.csv", "w", newline="", encoding="utf-8") as f: writer = csv.writer(f) writer.writerow(["STUDYID", "USUBJID", "RESCTRT"]) for row in dm: studyid = row.get("STUDYID") or "" usubjid = row.get("USUBJID") or "" entry = rescue.get((studyid, usubjid)) resctrt = entry[1] if entry else "" writer.writerow([studyid, usubjid, resctrt])if __name__ == "__main__": main()solutions/adam-adsl-rescue-med/result.sas
Edit22 lines/* opensas reference solution for the yamaa benchmark adam-adsl-rescue-med. Reads the benchmark inputs and derives the requested output. Execute with the existing opensas runtime: opensas /app/output/result.sas. */data cm; length STUDYID USUBJID CMTRT CMCAT CMSTDTC $1024; infile "/app/input/cm.csv" dsd dlm="," firstobs=2 truncover lrecl=32767; input STUDYID : $char1024. USUBJID : $char1024. CMSEQ CMTRT : $char1024. CMCAT : $char1024. CMSTDTC : $char1024.;run;data dm; length STUDYID USUBJID $1024; infile "/app/input/dm.csv" dsd dlm="," firstobs=2 truncover lrecl=32767; input STUDYID : $char1024. USUBJID : $char1024.;run;data rescue; set cm; if CMCAT='RESCUE MEDICATION'; nodate=missing(CMSTDTC); run;proc sort data=rescue; by STUDYID USUBJID nodate CMSTDTC CMSEQ; run;data firstcm; set rescue; by STUDYID USUBJID; if first.USUBJID; run;proc sql; create table result as select a.*,b.CMTRT as RESCTRT from dm as a left join firstcm as b on a.STUDYID=b.STUDYID and a.USUBJID=b.USUBJID; quit;proc export data=result(keep=STUDYID USUBJID RESCTRT) outfile="/app/output/adsl.csv" dbms=csv replace; run;
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